C. Estrella
Biology 4
1.
Summarize the
experiments performed by the following scientists, which provided evidence that
DNA is the genetic material:
Frederick Griffith, Alfred Hershey and Martha Chase, and Erwin Chrgaff.
2.
List the three
components of a nucleotide.
3.
Distinguish between
deoxyribose and ribose.
4.
List the nitrogen bases
found in DNA, and distinguish between pyrimidine and purine.
5.
Explain how Watson and
crick deduced the structure of DNA, and what evidence they used.
6.
Explain the
“base-pairing rule and describe its significance.
7.
Describe the structure
of DNA, and explain what kind of chemical bond connects the nucleotides of each
strand and what type of bond holds the two strands together.
8.
Explain, in your own
words, semiconservative replication, and describe the Meselson-Stahl experiment
(using isotopes of nitrogen in the culture medium and centrifuging between
replications).
9.
Describe the process of
DNA replication, and explain the role of helicase, DNA polymerase, ligase, and
primase.
10. Explain what energy source drives endergonic synthesis
of DNA.
11. Define antiparallel, and explain why continuous
synthesis of both DNA strands is not possible.
12. Distinguish between the leading strand and the lagging
strand.
13. Explain how the lagging strand is synthesized when DNA
polymerase can add nucleotides only to the 3’ end.